introduction : due to the importance of laser light penetration and propagation in biological tissues, many researchers have proposed several numerical methods such as monte carlo, finite element and green function methods. among them, the monte carlo method is an accurate method which can be applied for different tissues. however, because of its statistical nature, monte carlo simulation requi...

The Image reconstruction is an important problem in optical tomography. The process of the image processing requires the study of photon migration in biological tissue. There are several approaches to study and simulate propagation of photons in biological tissues. These approaches are categorized into stochastic and analytical groups. The Monte Carlo method as a stochastic method is widely use...

background : near infrared spectroscopy imaging is one of the new techniques used for investigating structural and functionality of different body tissues. this is done by injecting light into the medium and measuring the photon intensity at the surface of the tissue. method : in this paper the different medical applications, various imaging and simulation techniques of nirs imaging is describe...

General-purpose computing on graphics processing units (GPGPU) is shown to dramatically increase the speed of Monte Carlo simulations of photon migration. In a standard simulation of time-resolved photon migration in a semi-infinite geometry, the proposed methodology executed on a low-cost graphics processing unit (GPU) is a factor 1000 faster than simulation performed on a single standard proc...

We describe a novel Monte Carlo code for photon migration through 3D media with spatially varying optical properties. The code is validated against analytic solutions of the photon diffusion equation for semi-infinite homogeneous media. The code is also cross-validated for photon migration through a slab with an absorbing heterogeneity. A demonstration of the utility of the code is provided by ...

BACKGROUND Sublethal photon irradiation was recently suspected to increase tumor cell motility and promote locoregional recurrence of disease. This study was set up to describe mechanisms underlying increased glioma cell migration through photon irradiation and to analyse the modifiability of photon-altered glioma cell motility by integrin inhibition. METHODS Eight μm pore size membranes were...

Background: Near infrared spectroscopy imaging is one of the new techniques used for investigating structural and functionality of different body tissues. This is done by injecting light into the medium and measuring the photon intensity at the surface of the tissue.Method: In this paper the different medical applications, various imaging and simulation techniques of NIRS imaging is described. ...

We demonstrate the use of Monte Carlo simulations to generate photon scattering density functions (PSDFs) that represent the tissue volume sampled by steady-state and frequency-domain photon migration. We use these results to illustrate how scaling laws can be developed to determine the mean sampling depth of the multiply scattered photons detected by photon migration methods that remain valid ...

BACKGROUND Low-dose photon irradiation has repeatedly been suspected to increase a risk of promoting local recurrence of disease or even systemic dissemination. The purpose of this study was to investigate the motility of malignant pleural mesothelioma (MPM) cell lines after low-doses of photon irradiation and to elucidate the mechanism of the detected phenotype. METHODS H28 and H226 MPM cell...